BDBM50048051 7-Adamantan-2-ylmethyl-2-amino-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one::CHEMBL298954

SMILES Nc1nc2c(CC3C4CC5CC(C4)CC3C5)c[nH]c2c(=O)[nH]1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50048051   

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048051(7-Adamantan-2-ylmethyl-2-amino-3,5-dihydro-pyrrolo...)
Affinity DataIC50: 90nMAssay Description:In vitro inhibition of purine nucleoside phosphorylase from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048051(7-Adamantan-2-ylmethyl-2-amino-3,5-dihydro-pyrrolo...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of purine nucleoside phosphorylase from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed