BDBM50047971 CHEMBL3314865

SMILES Nc1ccccc1NC(=O)\C=C\c1ccc(cc1)-c1nnc(Cc2ccc3ccccc3c2)o1

InChI Key InChIKey=MBVDRTDKRGVQLM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50047971   

TargetHistone deacetylase 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50047971(CHEMBL3314865)
Affinity DataIC50: 2.40E+3nMT: 2°CAssay Description:Inhibition of human recombinant HDAC1 using histone H3 substrate pre-incubated at room temperature for 15 mins before substrate addition by fluorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50047971(CHEMBL3314865)
Affinity DataIC50: 2.00E+4nMT: 2°CAssay Description:Inhibition of human recombinant HDAC4 using non-histone trifluoroacetyl lysine substrate pre-incubated at room temperature for 15 mins before substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50047971(CHEMBL3314865)
Affinity DataIC50: 2.00E+4nMT: 2°CAssay Description:Inhibition of human recombinant HDAC6 pre-incubated at room temperature for 15 min before substrate addition by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed