BDBM50047238 3-(2,6-Dioxo-3-propyl-2,3,6,7-tetrahydro-purin-1-yl)-propionitrile::CHEMBL32241

SMILES CCCn1c2nc[nH]c2c(=O)n(CCC#N)c1=O

InChI Key InChIKey=LKBIUYWBMAWDON-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50047238   

TargetAdenosine receptor A1(Guinea pig)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50047238(3-(2,6-Dioxo-3-propyl-2,3,6,7-tetrahydro-purin-1-y...)
Affinity DataKi:  1.59E+4nMAssay Description:Binding affinity against Adenosine A1 receptor of cerebral cortex using [3H]-CPXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50047238(3-(2,6-Dioxo-3-propyl-2,3,6,7-tetrahydro-purin-1-y...)
Affinity DataKi:  4.08E+4nMAssay Description:Inhibition of cyclic AMP-phosphodiesterase ( PDE) in the supernatant of tracheal muscle homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50047238(3-(2,6-Dioxo-3-propyl-2,3,6,7-tetrahydro-purin-1-y...)
Affinity DataKi:  1.62E+5nMAssay Description:Binding affinity against adenosine A2 receptor of striatal membrane using [3H]CGS-21680 as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed