BDBM50047143 1,2,3,4,4a,5,6,10b-Octahydro-benzo[f]quinolin-7-ol::BDBM50452346::CHEMBL56519

SMILES [H][C@]12CCc3c(O)cccc3[C@]1([H])CCCN2

InChI Key InChIKey=RWDHALOKAOEZPC-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50047143   

TargetD(2) dopamine receptor(Rat)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50047143(CHEMBL56519 | BDBM50452346 | 1,2,3,4,4a,5,6,10b-Oc...)
Affinity DataIC50: 92nMAssay Description:Binding affinity against Dopamine receptor D2 using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50047143(CHEMBL56519 | BDBM50452346 | 1,2,3,4,4a,5,6,10b-Oc...)
Affinity DataIC50: 3.61E+3nMAssay Description:In vitro for binding affinity against sigma receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50047143(CHEMBL56519 | BDBM50452346 | 1,2,3,4,4a,5,6,10b-Oc...)
Affinity DataKi:  11nMAssay Description:Compound was tested for agonistic activity against D2 receptor from cloned CHO cells, used [3H]U-86170 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50047143(CHEMBL56519 | BDBM50452346 | 1,2,3,4,4a,5,6,10b-Oc...)
Affinity DataKi:  38nMAssay Description:Compound was tested for antagonistic activity against D2 receptor from rat striatum, used [3H]raclopride as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50047143(CHEMBL56519 | BDBM50452346 | 1,2,3,4,4a,5,6,10b-Oc...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor from bovine hippocampus, used [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed