BDBM50047090 3-{1-[3-(1,1-Dioxo-1H-1lambda*6*-naphtho[1,8-cd]isothiazol-2-yl)-propyl]-1,2,3,6-tetrahydro-pyridin-4-yl}-1H-indol-5-ol::CHEMBL19652

SMILES Oc1ccc2[nH]cc(C3=CCN(CCCN4c5cccc6cccc(c56)S4(=O)=O)CC3)c2c1

InChI Key InChIKey=PXLJHRMPQADPTF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50047090   

TargetD(2) dopamine receptor(Rat)
Centre De Recherches De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50047090(3-{1-[3-(1,1-Dioxo-1H-1lambda*6*-naphtho[1,8-cd]is...)
Affinity DataIC50: 10nMAssay Description:Binding affinity at dopamine receptor D2 by the inhibition of binding to [3H]spiperone in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Centre De Recherches De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50047090(3-{1-[3-(1,1-Dioxo-1H-1lambda*6*-naphtho[1,8-cd]is...)
Affinity DataIC50: 25nMAssay Description:Inhibition of [3H]peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed