BDBM50047088 2-{2-[4-(3H-Inden-1-ylmethyl)-piperidin-1-yl]-ethyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL416544

SMILES O=S1(=O)N(CCN2CCC(CC3=CCc4ccccc34)CC2)c2cccc3cccc1c23

InChI Key InChIKey=LUENHUWMNYJIAU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50047088   

TargetSodium-dependent serotonin transporter(Rat)
Centre De Recherches De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50047088(2-{2-[4-(3H-Inden-1-ylmethyl)-piperidin-1-yl]-ethy...)
Affinity DataIC50: 5nMAssay Description:Inhibition of [3H]peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Centre De Recherches De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50047088(2-{2-[4-(3H-Inden-1-ylmethyl)-piperidin-1-yl]-ethy...)
Affinity DataIC50: 100nMAssay Description:Binding affinity at dopamine receptor D2 by the inhibition of binding to [3H]spiperone in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed