BDBM50047084 10-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-10H-9-thia-10-aza-phenanthrene 9,9-dioxide::CHEMBL19226

SMILES Fc1ccc2[nH]cc(CC3CCN(CCN4c5ccccc5-c5ccccc5S4(=O)=O)CC3)c2c1

InChI Key InChIKey=UIVOCYXCNVVBDJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50047084   

TargetD(2) dopamine receptor(Rat)
Centre De Recherches De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50047084(10-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-...)
Affinity DataIC50: 100nMAssay Description:Binding affinity at dopamine receptor D2 by the inhibition of binding to [3H]spiperone in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Centre De Recherches De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50047084(10-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-...)
Affinity DataIC50: 35nMAssay Description:Inhibition of [3H]peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed