BDBM50047009 1-Methyl-9H-beta-carbolin-7-ol::1-Methyl-9H-beta-carbolin-7-ol (harmalol)::1-methyl-9H-pyrido[3,4-b]indol-7-ol::CHEMBL14285::CHEMBL1535235

SMILES Cc1c2c(ccn1)c3ccc(cc3[nH]2)O

InChI Key InChIKey=SATMZMMKDDTOSQ-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50047009   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Macquarie University

Curated by ChEMBL
LigandPNGBDBM50047009(CHEMBL1535235 | 1-methyl-9H-pyrido[3,4-b]indol-7-o...)
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of IDO1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Naresuan University

Curated by ChEMBL
LigandPNGBDBM50047009(CHEMBL1535235 | 1-methyl-9H-pyrido[3,4-b]indol-7-o...)
Affinity DataIC50: 8.02E+3nMAssay Description:Inhibition of electric eel AChE using acetylcholine iodide as substrate measured every 5 sec for 2 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50047009(CHEMBL1535235 | 1-methyl-9H-pyrido[3,4-b]indol-7-o...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant full length GST-tagged DYRK1A expressed in baculovirus expression system assessed as decrease in tau phosphorylation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
Xinyang Normal University

Curated by ChEMBL
LigandPNGBDBM50047009(CHEMBL1535235 | 1-methyl-9H-pyrido[3,4-b]indol-7-o...)
Affinity DataIC50: 770nMAssay Description:Inhibition of HASPIN (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed