BDBM50046950 CHEMBL3319244

SMILES Clc1ccc(NC(=O)c2ccc3[nH]ncc3c2)cc1Cl

InChI Key InChIKey=IQCPUPDYBUPHRL-UHFFFAOYSA-N

Data  1 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50046950   

TargetAmine oxidase [flavin-containing] B(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50046950(CHEMBL3319244)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of rat recombinant MAO-B expressed in baculovirus-infected insect cells using p-tyraimne substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50046950(CHEMBL3319244)
Affinity DataIC50: 0.586nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus-infected insect cells using p-tyraimne substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50046950(CHEMBL3319244)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat recombinant MAO-A expressed in baculovirus-infected insect cells using p-tyraimne substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50046950(CHEMBL3319244)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAOA in Sprague-Dawley rat liver mitochondria using p-tyramine as substrate measured for 45 mins in presence of MAOB inhibitor selegili...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50046950(CHEMBL3319244)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of MAOB in Sprague-Dawley rat liver mitochondria using p-tyramine as substrate measured for 45 mins in presence of MAOA inhibitor clorgyli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50046950(CHEMBL3319244)
Affinity DataIC50: 0.586nMAssay Description:Inhibition of recombinant human MAOB expressed in baculovirus-infected BTI insect cells using p-tyramine as substrate measured for 45 mins in presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50046950(CHEMBL3319244)
Affinity DataIC50: 0.589nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as decrease in H2O2 production using p-tyr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50046950(CHEMBL3319244)
Affinity DataIC50: 0.586nMAssay Description:Inhibition of human MAO-BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50046950(CHEMBL3319244)
Affinity DataKi:  0.260nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as decrease in H2O2 production using p-tyr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed