BDBM50046914 2,6-Di-tert-butyl-4-[2-(5-methylsulfanyl-[1,3,4]thiadiazol-2-yl)-vinyl]-phenol::CHEMBL275445

SMILES CSc1nnc(\C=C\c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)s1

InChI Key InChIKey=XYDNKMMWPPZSKC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50046914   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50046914(2,6-Di-tert-butyl-4-[2-(5-methylsulfanyl-[1,3,4]th...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-lipoxygenase measured by the reduction of leukotriene B4 (LTB4) in intact basophilic rat leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed