BDBM50046658 6-Methoxy-2-methyl-5-(pyridin-4-ylsulfanyl)-3H-quinazolin-4-one::CHEMBL164289

SMILES COc1ccc2nc(C)[nH]c(=O)c2c1Sc1ccncc1

InChI Key InChIKey=IDCGBCGEKKOBFY-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50046658   

TargetThymidylate synthase(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046658(6-Methoxy-2-methyl-5-(pyridin-4-ylsulfanyl)-3H-qui...)
Affinity DataKi:  260nMAssay Description:Inhibition of human Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046658(6-Methoxy-2-methyl-5-(pyridin-4-ylsulfanyl)-3H-qui...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of purified Escherichia coli Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046658(6-Methoxy-2-methyl-5-(pyridin-4-ylsulfanyl)-3H-qui...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of purified Escherichia coli Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046658(6-Methoxy-2-methyl-5-(pyridin-4-ylsulfanyl)-3H-qui...)
Affinity DataKi:  3.90E+3nMAssay Description:Inhibition of purified Escherichia coli Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed