BDBM50046645 5-(4-Benzenesulfonyl-phenylsulfanyl)-2,6-dimethyl-3H-quinazolin-4-one::CHEMBL423282

SMILES Cc1nc2ccc(C)c(Sc3ccc(cc3)S(=O)(=O)c3ccccc3)c2c(=O)[nH]1

InChI Key InChIKey=KYXGMQCZCITEBX-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50046645   

TargetThymidylate synthase(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046645(5-(4-Benzenesulfonyl-phenylsulfanyl)-2,6-dimethyl-...)
Affinity DataKi:  76nMAssay Description:Inhibition of human Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046645(5-(4-Benzenesulfonyl-phenylsulfanyl)-2,6-dimethyl-...)
Affinity DataKi:  96nMAssay Description:Inhibition of purified Escherichia coli Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046645(5-(4-Benzenesulfonyl-phenylsulfanyl)-2,6-dimethyl-...)
Affinity DataKi:  120nMAssay Description:Inhibition of human Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046645(5-(4-Benzenesulfonyl-phenylsulfanyl)-2,6-dimethyl-...)
Affinity DataKi:  220nMAssay Description:Inhibition of purified Escherichia coli Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed