BDBM50046397 CHEMBL3314412

SMILES CSC(=O)N(C)CCc1c[nH]c2ccccc12

InChI Key InChIKey=ASGGNXXOFLVYSB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50046397   

TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rat)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50046397(CHEMBL3314412)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of 60 mM K+-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rat)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50046397(CHEMBL3314412)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of 30 mM K+-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rat)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50046397(CHEMBL3314412)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of phenylephrine-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rat)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50046397(CHEMBL3314412)
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of L-type calcium channel in endothelium-intact Wistar rat aorta rings assessed as relaxation of 30 mM K+-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rat)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50046397(CHEMBL3314412)
Affinity DataIC50: 2.51E+5nMAssay Description:Inhibition of L-type calcium channel in Wistar rat aorta rings assessed as reduction in L-type Ba(2+) current at Vh of -50 mVMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed