BDBM50046248 2-Amino-8-[(3-methyl-thiophen-2-ylmethyl)-amino]-1,9-dihydro-purin-6-one::CHEMBL350773

SMILES Cc1ccsc1CNc1nc2nc(N)[nH]c(=O)c2[nH]1

InChI Key InChIKey=VZJBSOZNPAOAMB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50046248   

TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046248(2-Amino-8-[(3-methyl-thiophen-2-ylmethyl)-amino]-1...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed