BDBM50046246 2-Amino-8-[(thiophen-2-ylmethyl)-amino]-1,9-dihydro-purin-6-one::CHEMBL351228

SMILES Nc1nc2nc(NCc3cccs3)[nH]c2c(=O)[nH]1

InChI Key InChIKey=ASPRVQARSFBOHF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50046246   

TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046246(2-Amino-8-[(thiophen-2-ylmethyl)-amino]-1,9-dihydr...)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed