BDBM50046233 2-Amino-7-(3-fluoro-benzyl)-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one::CHEMBL159908

SMILES Nc1nc2c(Cc3cccc(F)c3)c[nH]c2c(=O)[nH]1

InChI Key InChIKey=WOWBUNTUMYSYSI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50046233   

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046233(2-Amino-7-(3-fluoro-benzyl)-3,5-dihydro-pyrrolo[3,...)
Affinity DataIC50: 220nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046233(2-Amino-7-(3-fluoro-benzyl)-3,5-dihydro-pyrrolo[3,...)
Affinity DataIC50: 24nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed