BDBM50046215 2,8-Diamino-9-thiophen-2-ylmethyl-1,9-dihydro-purin-6-one::CHEMBL162255

SMILES NC1Nc2c(nc(N)[nH]c2=O)N1Cc1cccs1

InChI Key InChIKey=QBNDMLFHVRRQSV-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50046215   

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046215(2,8-Diamino-9-thiophen-2-ylmethyl-1,9-dihydro-puri...)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046215(2,8-Diamino-9-thiophen-2-ylmethyl-1,9-dihydro-puri...)
Affinity DataKi:  45nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046215(2,8-Diamino-9-thiophen-2-ylmethyl-1,9-dihydro-puri...)
Affinity DataKi:  90nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed