BDBM50045247 3-((R)-2-Acetylamino-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-((S)-(S)-1-carboxy-2-(S)-1H-indol-3-yl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-2-methyl-butyl}-succinamic acid::Ac-D-Phe-Ile-Ile-Trp::CHEMBL312916

SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O

InChI Key InChIKey=KSMIQAULFAKWPP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50045247   

TargetEndothelin receptor type B(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50045247(Ac-D-Phe-Ile-Ile-Trp | 3-((R)-2-Acetylamino-3-phen...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]ET1 from Endothelin B receptor of rat cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50045247(Ac-D-Phe-Ile-Ile-Trp | 3-((R)-2-Acetylamino-3-phen...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]-ET-1 from Endothelin A receptor of rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50045247(Ac-D-Phe-Ile-Ile-Trp | 3-((R)-2-Acetylamino-3-phen...)
Affinity DataIC50: 1.00E+4nMAssay Description:Effective concentration against ET A receptor from rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetEndothelin receptor type B(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50045247(Ac-D-Phe-Ile-Ile-Trp | 3-((R)-2-Acetylamino-3-phen...)
Affinity DataIC50: 1.00E+4nMAssay Description:Effective concentration against Endothelin B receptor from rat cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed