BDBM50044890 8-Chloro-1,4,5,6-tetrahydro-2H-benzo[f]quinolin-3-one::CHEMBL277664

SMILES Clc1ccc2C3=C(CCc2c1)NC(=O)CC3

InChI Key InChIKey=HPNWYKAOJZXFSL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50044890   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50044890(8-Chloro-1,4,5,6-tetrahydro-2H-benzo[f]quinolin-3-...)
Affinity DataIC50: 460nMAssay Description:Inhibitory concentration was tested on human 5-alpha reductase 1 isozymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50044890(8-Chloro-1,4,5,6-tetrahydro-2H-benzo[f]quinolin-3-...)
Affinity DataIC50: 460nMAssay Description:In vitro inhibition of DHT production in Hs 68 (human genital fibroblast) cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed