BDBM50044644 CHEMBL3311472

SMILES ONC(=O)CCCCCCNC(=O)c1ccc2NC(=O)CCc2c1

InChI Key InChIKey=ITSLNGBJYKFUFZ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50044644   

TargetHistone deacetylase 2(Human)
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044644(CHEMBL3311472)
Affinity DataIC50: 20nMAssay Description:Inhibition of human HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044644(CHEMBL3311472)
Affinity DataIC50: 85nMAssay Description:Inhibition of human HDAC3 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044644(CHEMBL3311472)
Affinity DataIC50: 53nMAssay Description:Inhibition of human HDAC8 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044644(CHEMBL3311472)
Affinity DataIC50: 120nMAssay Description:Inhibition of human HDAC4 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044644(CHEMBL3311472)
Affinity DataIC50: 35nMAssay Description:Inhibition of human HDAC9 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044644(CHEMBL3311472)
Affinity DataIC50: 430nMAssay Description:Inhibition of human HDAC6 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044644(CHEMBL3311472)
Affinity DataIC50: 24nMAssay Description:Inhibition of human HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed