BDBM50044639 CHEMBL3309300

SMILES CC1(C)CC(=O)Nc2ccc(cc12)C(=O)NC[C@@H]1CC[C@H](CCC(=O)NO)CC1

InChI Key InChIKey=VGDKNUOQFCSMED-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50044639   

TargetHistone deacetylase 1(Human)
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044639(CHEMBL3309300)
Affinity DataIC50: 41nMAssay Description:Inhibition of human HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044639(CHEMBL3309300)
Affinity DataIC50: 25nMAssay Description:Inhibition of human HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044639(CHEMBL3309300)
Affinity DataIC50: 87nMAssay Description:Inhibition of human HDAC3 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044639(CHEMBL3309300)
Affinity DataIC50: 24nMAssay Description:Inhibition of human HDAC8 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044639(CHEMBL3309300)
Affinity DataIC50: 330nMAssay Description:Inhibition of human HDAC4 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044639(CHEMBL3309300)
Affinity DataIC50: 50nMAssay Description:Inhibition of human HDAC9 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044639(CHEMBL3309300)
Affinity DataIC50: 530nMAssay Description:Inhibition of human HDAC6 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed