BDBM50044303 CHEMBL3357439

SMILES CC(C)S(=O)(=O)c1ccccc1Nc1nc(Nc2cccc(NC(=O)CN)c2)ncc1Cl

InChI Key InChIKey=BDVGHJLTQZVVPA-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50044303   

TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50044303(CHEMBL3357439)
Affinity DataIC50: 153nMAssay Description:Inhibition of c-Met kinase (unknown origin) after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50044303(CHEMBL3357439)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of ALK (unknown origin) after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50044303(CHEMBL3357439)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of AXL (unknown origin) after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50044303(CHEMBL3357439)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Mer (unknown origin) after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50044303(CHEMBL3357439)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PDGFR-alpha (unknown origin) after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50044303(CHEMBL3357439)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PDGFR-beta (unknown origin) after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50044303(CHEMBL3357439)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR (unknown origin) after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50044303(CHEMBL3357439)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of c-Src (unknown origin) after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50044303(CHEMBL3357439)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KDR (unknown origin) after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50044303(CHEMBL3357439)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Flt-1 (unknown origin) after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50044303(CHEMBL3357439)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of c-Kit (unknown origin) after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50044303(CHEMBL3357439)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ABL (unknown origin) after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50044303(CHEMBL3357439)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of recombinant ALK (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50044303(CHEMBL3357439)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of recombinant ALK (unknown origin) using poly (Glu,Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2020
Entry Details Article
PubMed