BDBM50044251 CHEMBL3314037::US9321750, 2

SMILES CC(=O)Nc1ccc2N(Cc3ccc(cc3)C(O)(C(F)(F)F)C(F)(F)F)CCCc2c1

InChI Key InChIKey=KXOOBRHIKIGXPJ-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50044251   

TargetNuclear receptor ROR-gamma(Human)
Innov17

US Patent
LigandPNGBDBM50044251(US9321750, 2 | CHEMBL3314037)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound binding to the human RORγ LBD was assessed using the Human RORγ Assay System (INDIGO Biosciences Inc.) as per manufacturer's i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Innov17

US Patent
LigandPNGBDBM50044251(US9321750, 2 | CHEMBL3314037)
Affinity DataEC50: <1.00E+4nMAssay Description:Inverse agonist activity at human RoRc in human skin model assessed as suppression of IL-17F level relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Innov17

US Patent
LigandPNGBDBM50044251(US9321750, 2 | CHEMBL3314037)
Affinity DataEC50: <1.00E+4nMAssay Description:Inverse agonist activity at human RoRc in human skin model assessed as suppression of IL-17A level relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed