BDBM50044079 5-[1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-meth-(Z)-ylidene]-4-oxo-4,5-dihydro-thiazol-2-yl-cyanamide::CHEMBL16048

SMILES CC(C)(C)c1cc(C=C2SC(NC#N)=NC2=O)cc(c1O)C(C)(C)C

InChI Key InChIKey=QHJVYZBKWNABSG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50044079   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50044079(5-[1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-meth-(Z)...)
Affinity DataIC50: 630nMAssay Description:Inhibition of 5-lipoxygenase in intact rat basophilic leukemia cells stimulated with the calcium ionophore A-23187More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50044079(5-[1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-meth-(Z)...)
Affinity DataIC50: 2.00E+4nMAssay Description:IC50 against Prostaglandin G/H synthase 1 from human platelet rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50044079(5-[1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-meth-(Z)...)
Affinity DataIC50: 230nMAssay Description:IC50 value was determined against Prostaglandin G/H synthase 2 of J7744A.1 cell lines.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50044079(5-[1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-meth-(Z)...)
Affinity DataIC50: 5.50E+4nMAssay Description:IC50 against recombinant human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed