BDBM50044078 2-Hydroxy-5-[1-(4-hydroxy-3,5-diisopropyl-phenyl)-meth-(Z)-ylidene]-thiazol-4-one::CHEMBL325065

SMILES CC(C)c1cc(\C=C2/SC(=O)NC2=O)cc(C(C)C)c1O

InChI Key InChIKey=PJHWHESCEXNAHD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044078   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50044078(2-Hydroxy-5-[1-(4-hydroxy-3,5-diisopropyl-phenyl)-...)
Affinity DataIC50: 220nMAssay Description:Inhibition of 5-lipoxygenase in intact rat basophilic leukemia cells stimulated with the calcium ionophore A-23187More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed