BDBM50044074 CHEMBL113138::CHEMBL15781::N-{5-[1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-meth-(Z)-ylidene]-4-oxo-4,5-dihydro-oxazol-2-yl}-guanidine; compound with methanesulfonic acid

SMILES CC(C)(C)c1cc(C=C2OC(NC(N)=N)=NC2=O)cc(c1O)C(C)(C)C

InChI Key InChIKey=FDKQQLIDPCZUFH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50044074   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50044074(CHEMBL113138 | CHEMBL15781 | N-{5-[1-(3,5-Di-tert-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of 5-lipoxygenase in intact rat basophilic leukemia cells stimulated with the calcium ionophore A-23187More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50044074(CHEMBL113138 | CHEMBL15781 | N-{5-[1-(3,5-Di-tert-...)
Affinity DataIC50: 4.40E+3nMAssay Description:IC50 against Prostaglandin G/H synthase 1 from human platelet rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50044074(CHEMBL113138 | CHEMBL15781 | N-{5-[1-(3,5-Di-tert-...)
Affinity DataIC50: 440nMAssay Description:IC50 value was determined against Prostaglandin G/H synthase 2 of J7744A.1 cell lines.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50044074(CHEMBL113138 | CHEMBL15781 | N-{5-[1-(3,5-Di-tert-...)
Affinity DataIC50: 1.20E+3nMAssay Description:IC50 against ovine Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50044074(CHEMBL113138 | CHEMBL15781 | N-{5-[1-(3,5-Di-tert-...)
Affinity DataIC50: 5.10E+3nMAssay Description:IC50 against recombinant human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed