BDBM50044064 5-[1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-eth-(Z)-ylidene]-2-hydroxy-thiazol-4-one::CHEMBL113525

SMILES C\C(=C1\SC(=O)NC1=O)c1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C

InChI Key InChIKey=HZYSIBNRDWCXBF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044064   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50044064(5-[1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-eth-(Z)-...)
Affinity DataIC50: 480nMAssay Description:Inhibition of 5-lipoxygenase in intact rat basophilic leukemia cells stimulated with the calcium ionophore A-23187More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed