BDBM50043856 (Z)-6-{5-[2-(4-Fluoro-benzenesulfonylamino)-ethyl]-1-methyl-1H-pyrrol-2-yl}-6-pyridin-3-yl-hex-5-enoic acid::CHEMBL339812

SMILES Cn1c(CCNS(=O)(=O)c2ccc(F)cc2)ccc1\C(=C/CCCC(O)=O)c1cccnc1

InChI Key InChIKey=PWJROBCGVCOUEB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043856   

TargetThromboxane-A synthase(Human)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043856((Z)-6-{5-[2-(4-Fluoro-benzenesulfonylamino)-ethyl]...)
Affinity DataIC50: 4nMAssay Description:Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043856((Z)-6-{5-[2-(4-Fluoro-benzenesulfonylamino)-ethyl]...)
Affinity DataIC50: 230nMAssay Description:Displacement of the high affinity radiolabeled ligand [3H]- SQ-29548 from the PGH-2/TXA-2 receptor in human gel-filtered platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed