BDBM50043852 (E)-6-(4-{2-[Carbamoylmethyl-(4-chloro-benzenesulfonyl)-amino]-ethyl}-phenyl)-6-pyridin-3-yl-hex-5-enoic acid::CHEMBL126196

SMILES NC(=O)CN(CCc1ccc(cc1)C(=C/CCCC(O)=O)\c1cccnc1)S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=KEOWJWUNPZAGBC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043852   

TargetThromboxane A2 receptor(Human)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043852((E)-6-(4-{2-[Carbamoylmethyl-(4-chloro-benzenesulf...)
Affinity DataIC50: 49nMAssay Description:Displacement of the high affinity radiolabeled ligand [3H]- SQ-29548 from the PGH-2/TXA-2 receptor in human gel-filtered platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043852((E)-6-(4-{2-[Carbamoylmethyl-(4-chloro-benzenesulf...)
Affinity DataIC50: 5nMAssay Description:Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed