BDBM50043848 (E)-6-Pyridin-3-yl-6-{4-[2-(4-trifluoromethyl-benzenesulfonylamino)-ethyl]-phenyl}-hex-5-enoic acid::CHEMBL338360

SMILES OC(=O)CCC\C=C(/c1ccc(CCNS(=O)(=O)c2ccc(cc2)C(F)(F)F)cc1)c1cccnc1

InChI Key InChIKey=KVNYICIYEISPHS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043848   

TargetThromboxane-A synthase(Human)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043848((E)-6-Pyridin-3-yl-6-{4-[2-(4-trifluoromethyl-benz...)
Affinity DataIC50: 6nMAssay Description:Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043848((E)-6-Pyridin-3-yl-6-{4-[2-(4-trifluoromethyl-benz...)
Affinity DataIC50: 28nMAssay Description:Displacement of the high affinity radiolabeled ligand [3H]- SQ-29548 from the PGH-2/TXA-2 receptor in human gel-filtered platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed