BDBM50043845 (E)-6-[4-(2-Phenylmethanesulfonylamino-ethyl)-phenyl]-6-pyridin-3-yl-hex-5-enoic acid::CHEMBL127357

SMILES OC(=O)CCC\C=C(/c1ccc(CCNS(=O)(=O)Cc2ccccc2)cc1)c1cccnc1

InChI Key InChIKey=GDADGKYHLMMBAW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043845   

TargetThromboxane A2 receptor(Human)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043845((E)-6-[4-(2-Phenylmethanesulfonylamino-ethyl)-phen...)
Affinity DataIC50: 260nMAssay Description:Displacement of the high affinity radiolabeled ligand [3H]- SQ-29548 from the PGH-2/TXA-2 receptor in human gel-filtered platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043845((E)-6-[4-(2-Phenylmethanesulfonylamino-ethyl)-phen...)
Affinity DataIC50: 5nMAssay Description:Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed