BDBM50043844 (E)-6-[4-(4-Chloro-benzenesulfonylamino)-phenyl]-6-pyridin-3-yl-hex-5-enoic acid::CHEMBL339568

SMILES OC(=O)CCC\C=C(/c1ccc(NS(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1

InChI Key InChIKey=XIMQLTCUQYUZQW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043844   

TargetThromboxane A2 receptor(Human)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043844((E)-6-[4-(4-Chloro-benzenesulfonylamino)-phenyl]-6...)
Affinity DataIC50: 270nMAssay Description:Displacement of the high affinity radiolabeled ligand [3H]- SQ-29548 from the PGH-2/TXA-2 receptor in human gel-filtered platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043844((E)-6-[4-(4-Chloro-benzenesulfonylamino)-phenyl]-6...)
Affinity DataIC50: 5nMAssay Description:Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed