BDBM50043824 4-Chloro-N-(2-{4-[(E)-1-pyridin-3-yl-5-(1H-tetrazol-5-yl)-pent-1-enyl]-phenyl}-ethyl)-benzenesulfonamide::CHEMBL126185

SMILES Clc1ccc(cc1)S(=O)(=O)NCCc1ccc(cc1)C(=CCCCc1nnn[nH]1)c1cccnc1

InChI Key InChIKey=LQZKCALSANZAMX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043824   

TargetThromboxane A2 receptor(Human)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043824(4-Chloro-N-(2-{4-[(E)-1-pyridin-3-yl-5-(1H-tetrazo...)
Affinity DataIC50: 12nMAssay Description:Displacement of the high affinity radiolabeled ligand [3H]- SQ-29548 from the PGH-2/TXA-2 receptor in human gel-filtered platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043824(4-Chloro-N-(2-{4-[(E)-1-pyridin-3-yl-5-(1H-tetrazo...)
Affinity DataIC50: 21nMAssay Description:Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed