BDBM50043823 (E)-6-(4-{2-[(4-Chloro-benzenesulfonyl)-methyl-amino]-ethyl}-phenyl)-6-pyridin-3-yl-hex-5-enoic acid::CHEMBL129355

SMILES CN(CCc1ccc(cc1)C(=C/CCCC(O)=O)\c1cccnc1)S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=RERMKDAOFJRCJU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043823   

TargetThromboxane A2 receptor(Human)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043823((E)-6-(4-{2-[(4-Chloro-benzenesulfonyl)-methyl-ami...)
Affinity DataIC50: 25nMAssay Description:Displacement of the high affinity radiolabeled ligand [3H]- SQ-29548 from the PGH-2/TXA-2 receptor in human gel-filtered platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043823((E)-6-(4-{2-[(4-Chloro-benzenesulfonyl)-methyl-ami...)
Affinity DataIC50: 15nMAssay Description:Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed