BDBM50043719 3-(2-{[(4R,10R,13S)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-10-benzyl-7-(3H-imidazol-4-ylmethyl)-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carbonyl]-amino}-hexanoylamino)-succinamic acid::CHEMBL2372214

SMILES CCCC[C@H](NC(=O)[C@H]1NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SSC1(C)C)C(=O)N[C@@H](CC(O)=O)C(N)=O

InChI Key InChIKey=PWZZAHNMTFDCLS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50043719   

TargetMu-type opioid receptor(Guinea pig)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50043719(3-(2-{[(4R,10R,13S)-13-[(S)-2-Amino-3-(4-hydroxy-p...)
Affinity DataIC50: 3.40nMAssay Description:In vitro inhibition of electrically evoked contractions in guinea pig ileum longitudinal muscle myenteric plexusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50043719(3-(2-{[(4R,10R,13S)-13-[(S)-2-Amino-3-(4-hydroxy-p...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of [3H]CTOP binding to rat brain homogenate mu-opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50043719(3-(2-{[(4R,10R,13S)-13-[(S)-2-Amino-3-(4-hydroxy-p...)
Affinity DataIC50: 3.40nMAssay Description:In vitro inhibition of electrically induced smooth muscle contractions of mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50043719(3-(2-{[(4R,10R,13S)-13-[(S)-2-Amino-3-(4-hydroxy-p...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of [3H][p-Cl-Phe-]DPDE binding to rat brain homogenate delta-opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed