BDBM50043714 CHEMBL288317::{(4S,7R,10S,13R)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-10-benzyl-4-[(R)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradec-7-yl}-acetic acid

SMILES CC(C)[C@@H](NC(=O)[C@@H]1NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SSC1(C)C)C(=O)NCC(N)=O

InChI Key InChIKey=CIXRLSHQKQIGJK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50043714   

TargetMu-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50043714({(4S,7R,10S,13R)-13-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of [3H]CTOP binding to rat brain homogenate mu-opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50043714({(4S,7R,10S,13R)-13-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50: 6.80E+4nMAssay Description:In vitro inhibition of electrically evoked contractions in guinea pig ileum longitudinal muscle myenteric plexusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50043714({(4S,7R,10S,13R)-13-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50: 6.30nMAssay Description:In vitro inhibition of electrically induced smooth muscle contractions of mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50043714({(4S,7R,10S,13R)-13-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of [3H][p-Cl-Phe-]DPDE binding to rat brain homogenate delta-opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed