BDBM50043675 5-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl]-thiazole::CHEMBL277035

SMILES COC1(CCc2ccc(OCc3ccc4ccccc4c3)cc12)c1cncs1

InChI Key InChIKey=OPSLGEKMOXAZEB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50043675   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50043675(5-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)
Affinity DataIC50: 500nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50043675(5-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50043675(5-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed