BDBM50043578 1N-phenyl-2-[1-amino-(1R)-ethylcarboxamido(phenyl)methylcarboxamido]-4-methyl-(2S)-pentanamide::CHEMBL2370820

SMILES CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@@H](C)N)c1ccccc1)C(=O)Nc1ccccc1

InChI Key InChIKey=LISPGQPSYLENBK-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50043578   

TargetStromelysin-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043578(1N-phenyl-2-[1-amino-(1R)-ethylcarboxamido(phenyl)...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human fibroblast stromelysinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043578(1N-phenyl-2-[1-amino-(1R)-ethylcarboxamido(phenyl)...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human fibroblast collagenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043578(1N-phenyl-2-[1-amino-(1R)-ethylcarboxamido(phenyl)...)
Affinity DataKi:  3.40E+4nMAssay Description:Inhibition of human fibroblast stromelysinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed