BDBM50043548 1-(4-Chloro-phenyl)-3-{1-[2-(4-methyl-piperazin-1-yl)-2-oxo-ethyl]-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl}-urea::CHEMBL342640

SMILES CN1CCN(CC1)C(=O)CN1c2ccccc2C(=NC(NC(=O)Nc2ccc(Cl)cc2)C1=O)c1ccccc1

InChI Key InChIKey=OTWUWDFMCIAVBR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50043548   

LigandPNGBDBM50043548(1-(4-Chloro-phenyl)-3-{1-[2-(4-methyl-piperazin-1-...)
Affinity DataIC50: 8nMAssay Description:Ability to inhibit the binding of [125I]CCK-8 to Cholecystokinin type B receptor in guinea pig cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50043548(1-(4-Chloro-phenyl)-3-{1-[2-(4-methyl-piperazin-1-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Ability to inhibit the binding of [125I]CCK-8 to Cholecystokinin type A receptor in rat pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50043548(1-(4-Chloro-phenyl)-3-{1-[2-(4-methyl-piperazin-1-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of binding of [125I]CCK-8 to cholecystokinin type A receptor in rat pancreatic tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
LigandPNGBDBM50043548(1-(4-Chloro-phenyl)-3-{1-[2-(4-methyl-piperazin-1-...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of binding of [125I]-CCK-8 to the cholecystokinin type B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
LigandPNGBDBM50043548(1-(4-Chloro-phenyl)-3-{1-[2-(4-methyl-piperazin-1-...)
Affinity DataIC50: 2.60nMAssay Description:Ability to inhibit the binding of [125I]-gastrin to gastric glands in guinea pig.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article