BDBM50043424 2-[5-(2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-4-ylmethyl)-indole-1-carbonyl]-6-nitro-benzonitrile::CHEMBL335323

SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc2n(ccc2c1)C(=O)c1ccccc1C#N

InChI Key InChIKey=FGIBVFGYWSDJPX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043424   

TargetType-1 angiotensin II receptor(Rabbit)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043424(2-[5-(2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridi...)
Affinity DataIC50: 250nMAssay Description:In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-2 angiotensin II receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043424(2-[5-(2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridi...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro antagonist activity against angiotensin II receptor type 2 in rat midbrain using [125I]-Sar,Ile AII.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed