BDBM50043372 (E)-1,8-Dihydroxy-10-[3-(4-nitro-phenyl)-acryloyl]-10H-anthracen-9-one::CHEMBL130581

SMILES Oc1cccc2C(C(=O)C=Cc3ccc(cc3)[N+]([O-])=O)c3cccc(O)c3C(=O)c12

InChI Key InChIKey=VIGFACAVDTVYPO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50043372   

Target5-lipoxygenase(Bovine)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50043372((E)-1,8-Dihydroxy-10-[3-(4-nitro-phenyl)-acryloyl]...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed