BDBM50043356 1,8-Dihydroxy-10-[2-(4-nitro-phenyl)-acetyl]-10H-anthracen-9-one::CHEMBL134069

SMILES Oc1cccc2C(C(=O)Cc3ccc(cc3)[N+]([O-])=O)c3cccc(O)c3C(=O)c12

InChI Key InChIKey=FTMIEKKGADRIGC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043356   

Target5-lipoxygenase(Bovine)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50043356(1,8-Dihydroxy-10-[2-(4-nitro-phenyl)-acetyl]-10H-a...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50043356(1,8-Dihydroxy-10-[2-(4-nitro-phenyl)-acetyl]-10H-a...)
Affinity DataIC50: 2.00E+3nMAssay Description:Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed