BDBM50043347 1,8-Dihydroxy-10-(3-phenyl-propylidene)-10H-anthracen-9-one::CHEMBL130382

SMILES [#8]-c1cccc2\[#6](=[#6]/[#6]-[#6]-c3ccccc3)-c3cccc(-[#8])c3-[#6](=O)-c12

InChI Key InChIKey=YHIITUKUQHTSFH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043347   

Target5-lipoxygenase(Bovine)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50043347(1,8-Dihydroxy-10-(3-phenyl-propylidene)-10H-anthra...)
Affinity DataIC50: 2.00E+3nMAssay Description:Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50043347(1,8-Dihydroxy-10-(3-phenyl-propylidene)-10H-anthra...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed