BDBM50043327 2-Hydroxy-5-(2-hydroxy-benzylamino)-benzoic acid methyl ester::CHEMBL132907

SMILES COC(=O)c1cc(NCc2ccccc2O)ccc1O

InChI Key InChIKey=GIAGGFBJOMQPDM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043327   

TargetEpidermal growth factor receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50043327(2-Hydroxy-5-(2-hydroxy-benzylamino)-benzoic acid m...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of EGF-dependent DNA synthesis in ER 22 cells incubated with [3H]TdRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNADPH oxidase 4(Human)
Vichem Chemie Research

Curated by ChEMBL
LigandPNGBDBM50043327(2-Hydroxy-5-(2-hydroxy-benzylamino)-benzoic acid m...)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of NOX4 expressed in HEK293 FS cells assessed as H2O2 production by H2O2/Tyr/LPO assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed