BDBM50043231 4-[2-(1H-Indol-3-yl)-1-methylcarbamoyl-ethylcarbamoyl]-3-mercapto-6-methyl-heptanoic acid methyl ester::CHEMBL128372

SMILES CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)[C@@H](S)CC(=O)OC

InChI Key InChIKey=RXFIBNVNUQIYSK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043231   

TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043231(4-[2-(1H-Indol-3-yl)-1-methylcarbamoyl-ethylcarbam...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of rat skin type I collagen degradation by purified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043231(4-[2-(1H-Indol-3-yl)-1-methylcarbamoyl-ethylcarbam...)
Affinity DataIC50: 21nMAssay Description:Inhibition of rat skin type I collagen degradation by purified human lung fibroblast collagenase without beta-mercaptoethanolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed