BDBM50043171 1N-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1,4'-(hexahydropyridine)]-1-ylsulfonylmethyl-(1S,2S,4R)-bicyclo[2.2.1]hept-2-yl]-2-amino-(2S)-pentanediamide::CHEMBL131650

SMILES CC1(C)[C@@H]2CC[C@@]1(CS(=O)(=O)N1CCC3(CCc4ccccc34)CC1)[C@H](C2)NC(=O)[C@@H](N)CCC(N)=O

InChI Key InChIKey=HUBWQAUQKKUZCD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50043171   

TargetVasopressin V2 receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043171(1N-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1,4...)
Affinity DataIC50: 5.10E+3nMAssay Description:Displacement of [3H]-AVP from binding to Vasopressin receptor V2 of rat kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043171(1N-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1,4...)
Affinity DataIC50: 2.30E+3nMAssay Description:Displacement of [3H]AVP from binding to arginine vasopressin 1a (V1a) column of rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxytocin receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043171(1N-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1,4...)
Affinity DataIC50: 55nMAssay Description:Tested against rat uterine OT receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043171(1N-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1,4...)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of radioligand [3H]-AVP binding to the vasopressin V2 receptor in rat kidney tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxytocin receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043171(1N-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1,4...)
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]OT from binding to oxytocin receptor of rat uterusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a/V1b receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043171(1N-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1,4...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of radioligand [3H]AVP binding to the vasopressin V1 receptor in rat liver tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed