BDBM50042994 (2E)-3-(3,4-dihydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one::CHEMBL127409::trans-2',3,4,4',6'-pentahydroxychalcone

SMILES Oc1cc(O)c(C(=O)\C=C\c2ccc(O)c(O)c2)c(O)c1

InChI Key InChIKey=CRBYNQCDRNZCNX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50042994   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Tokushima Bunri University

Curated by ChEMBL
LigandPNGBDBM50042994((2E)-3-(3,4-dihydroxyphenyl)-1-(2,4,6-trihydroxyph...)
Affinity DataIC50: 140nMAssay Description:In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Tokushima Bunri University

Curated by ChEMBL
LigandPNGBDBM50042994((2E)-3-(3,4-dihydroxyphenyl)-1-(2,4,6-trihydroxyph...)
Affinity DataIC50: 140nMAssay Description:Inhibition of 5-lipoxygenase in rat RBL1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article

TargetArginase-1(Bovine)
Universite de Franche-Comte

Curated by ChEMBL
LigandPNGBDBM50042994((2E)-3-(3,4-dihydroxyphenyl)-1-(2,4,6-trihydroxyph...)
Affinity DataIC50: 9.80E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed