BDBM50042646 7-[3-(3-Chloro-phenyl)-2-(4-fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-3,5-dihydroxy-hept-6-enoic acid methyl ester::CHEMBL120922

SMILES COC(=O)C[C@H](O)C[C@H](O)\C=C\n1c(cc(c1-c1ccc(F)cc1)-c1cccc(Cl)c1)C(C)C

InChI Key InChIKey=XJJSLIQTCQSYFK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50042646   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50042646(7-[3-(3-Chloro-phenyl)-2-(4-fluoro-phenyl)-5-isopr...)
Affinity DataIC50: 2nMAssay Description:Inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed