BDBM50042544 5-Butyl-2-(2-nitro-phenyl)-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2H-pyrazole-3-carboxylic acid::CHEMBL93547

SMILES CCCCc1nn(c(C(O)=O)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)-c1ccccc1[N+]([O-])=O

InChI Key InChIKey=QBAIFEHUMQOWLP-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50042544   

TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042544(5-Butyl-2-(2-nitro-phenyl)-4-[2'-(1H-tetrazol-5-yl...)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of metallo-beta-lactamase (MBL) from Bacteroides fragilis.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Pseudomonas aeruginosa)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042544(5-Butyl-2-(2-nitro-phenyl)-4-[2'-(1H-tetrazol-5-yl...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of metallo-beta-lactamase (MBL) from Pseudomonas aeruginosa mediated by the plasmid-borne IMP-1 enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Rabbit)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042544(5-Butyl-2-(2-nitro-phenyl)-4-[2'-(1H-tetrazol-5-yl...)
Affinity DataIC50: 1.70nMAssay Description:Evaluation of Angiotensin II antagonistic activity by displacement of [125I]-Sar Ile-AII at the rabbit aorta Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidase 1(Pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042544(5-Butyl-2-(2-nitro-phenyl)-4-[2'-(1H-tetrazol-5-yl...)
Affinity DataKi:  6.40E+5nMAssay Description:In vitro apparent inhibition constant of porcine renal Dehydropeptidase-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed