BDBM50042512 CHEMBL120454::N'-allyl-N-hydroxy-N-[(6-phenoxy-2H-chromen-3-yl)methyl]urea

SMILES ON(CC1=Cc2cc(Oc3ccccc3)ccc2OC1)C(=O)NCC=C

InChI Key InChIKey=KFNDCACNUFPHGC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50042512   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50042512(N'-allyl-N-hydroxy-N-[(6-phenoxy-2H-chromen-3-yl)m...)
Affinity DataIC50: 44nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase by reduction of LTB4 formed in guinea pig polymorphonuclear leukocytes (PMNs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50042512(N'-allyl-N-hydroxy-N-[(6-phenoxy-2H-chromen-3-yl)m...)
Affinity DataIC50: 37nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase by reduction of 5-hydroxyeicosatetraenoic acid (5-HETE) formed in guinea pig polymorphonuclear le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed